Edward and Alphonse Elric were children living in the rural village of Resembool in the country of Amestris. Their father Hohenheim, a talented alchemist, had left home when Edward was very young and Alphonse was still an infant. Years later, their mother, Trisha Elric, died of a terminal illness. After their mother's death, they lived with Winry and her grandmother until finding a teacher to teach them alchemy.